OBJECTIVES:: To understand the burden of Chronic Heart Failure (CHF) on caregivers in Brazil. METHODS:: A Disease Specific Program was conducted to assess the impact of CHF in Brazil. Data was made available through cardiologist-completed patient record forms, and patient and caregiver self-completion (CSC) questionnaires. RESULTS:: CSC questionnaires revealed that a typical caregiver (n=116) was female (63%) with a mean age of 56.8 years. Caregivers were mostly retired (47%); however 17% worked as a homemaker and 16% worked full-time. Nine in ten patients lived with the main caregiver, who was often the patients’ spouse (71%) or daughter/son (22%). Caregiver Activities: The most frequently reported tasks were reminding the patient to take medicine when required (70%), and emotional support/encouragement (66%). Caregivers most frequently asked doctors about best practices when caring for the patient (73%). Emotional Burden: The majority of caregivers had not made, and do not anticipate making, any lifestyle changes as a result of caring for the patient. However, one in ten reported a reduced amount of time given to other family members. As a result of caring for the patient, 24% of caregivers suffered from anxiety and 23% from stress. Financial Burden: One in ten caregivers reported a reduced income due to a job change or reduction in working hours as a result of caregiver responsibilities. Additionally, no caregivers received financial assistance from the health care system or social services. Overall, caregivers were not financially responsible for patients’ treatment, rehabilitation, and hospitalisation or travel costs. Travel: On average, caregivers accompanied patients 5 times per year to CHF appointments, and for those who reported travel costs (n=36), a mean cost of $10 per trip was incurred. CONCLUSIONS:: These data are significant for understanding the impact of CHF for patients’ caregivers, and extrapolating its impact to the greater Brazilian population.