Health States Utilities for Allergic Rhinitis - an AI-Supported Systematic Review
Author(s)
Borowiack E1, Sadowska E2, Nowak A3, Brozek J4
1Evidence Prime, Krakow, Poland, 2Evidence Prime, Cracow, Poland, 3Evidence Prime, Krakow, MA, Poland, 4McMaster University, Hamilton, ON, Canada
Presentation Documents
OBJECTIVES: Allergic rhinitis (AR) stands out as a prevalent and challenging health issue in modern societies.
Health state utility values (HSUVs) play a crucial role in quantifying the burden of this disease, and they are commonly used to inform economic analysis and determine the cost-effectiveness of technologies. The objective of this review was to build a comprehensive catalog of HSUVs for children and adults diagnosed with AR, identify evidence gaps and provide future directions for research in this area.METHODS: We searched bibliographic databases (Medline, Embase, PsycINFO, CINAHL) and gray literature for HSUVs for AR patients measured using direct and indirect preference elicitation approaches.
Laser AI, with its machine learning models, was utilized at all process steps, from records deduplication and prioritizing them for screening, to the data extraction stage.RESULTS: 9 studies (15 609 patients) met all eligibility criteria and reported HSUVs for 58 health states.
Research was primarily carried out in Europe and North America. There was no evidence for South America, Africa, or Australia. The majority of studies elicited HSUVs for adults only. EQ-5D were the most often used instrument. Standard Gamble was used in 3 studies, and Time Trade-Off in one study. We present the full data on all HSUVs. Children reported lower HSUVs compared to adult patients.CONCLUSIONS: This SR provides a dataset of HSUVs for AR that are required to support future economic studies. The use of AI allowed us to automate the deduplication of records and facilitated the screening and data extraction process.
The study populations, elicitation methods, and summary statistics exhibited significant heterogeneity, leading to a wide range of reported HSUVs. Further studies are needed to explore the HSUVs for children subgroups and patients from regions other than Europe and North America.Conference/Value in Health Info
Value in Health, Volume 27, Issue 6, S1 (June 2024)
Code
PCR115
Topic
Patient-Centered Research
Topic Subcategory
Health State Utilities, Patient-reported Outcomes & Quality of Life Outcomes
Disease
No Additional Disease & Conditions/Specialized Treatment Areas, Respiratory-Related Disorders (Allergy, Asthma, Smoking, Other Respiratory)