Burden of COVID-19 in Córdoba, A Department of Colombia: Results of Disability-Adjusted Life-Years

Abstract

Objectives

This study aimed to estimate the burden of acute COVID-19 in Córdoba, one of the most affected departments (states) in Colombia, through the estimation of disability-adjusted life-years (DALYs).

Methods

DALYs were estimated based on the number of cases of severe acute respiratory syndrome coronavirus 2 infection cases reported by official Colombian sources. A transition probability matrix among severity states was calculated using data obtained from a retrospective cohort that included 1736 COVID-19 confirmed subjects living in Córdoba.

Results

Córdoba had 120.23 deaths per 100 000 habitants during the study period (March 2020 to April 2021). Estimated total DALYs were 49 243 (2692 DALYs per 100 000 inhabitants), mostly attributed to fatal cases (99.7%). On average, 25 years of life were lost because of death by this infection. A relevant proportion of years of life lost because of COVID-19 (46.6%) was attributable to people 95% confidence interval 4.0-20.6).

Conclusion

In Córdoba, premature mortality because of COVID-19 was substantially represented by people 60 years old and was greater in males. Our data may be representative of Latin American populations with great infection spread during the first year of the pandemic and contribute to novel methodological aspects and parameter estimations that may be useful to measure COVID-19 burden in other countries of the region.

Authors

Ana Lozano Fernando Salcedo-Mejía Josefina Zakzuk Nelson Rafael Alvis-Zakzuk Lina Moyano-Tamara Héctor Serrano-Coll Bertha Gastelbondo Salim Mattar Nelson J. Alvis-Zakzuk Nelson Alvis-Guzman

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