The goal of this forum is to describe the current criteria employed to evaluate medication adherence enhancing interventions (MAEIs) and have forum participants be involved in the prioritization of these criteria. Medication non-adherence is prevalent across all clinical conditions causing major medical and economic challenges. While MAEIs have demonstrated proven benefits in improving outcomes, existing evidence on how to assess MAEIs remains limited. Important policy decisions about MAEIs are currently based on inadequate or suboptimal information, which further leads to poor quality / effectiveness of MAEIs. The ISPOR Medication Adherence and Persistence Special Interest Group (MAP-SIG) is conducting a systematic review of the evidence associated with MAEIs by identifying and prioritizing relevant criteria for their value assessment from the perspectives of different stakeholders such as healthcare providers, payers, patients, and policymakers. This forum will present the varying criteria for the evaluation of MAEIs based on most up-to-date results of a systematic literature review. The forum leaders will discuss criteria considered for the assessment of MAEIs in clinical trials, prospective observational studies, and economic evaluations. Discussion will be followed by an audience participation, which will include an assessment of the identified criteria through ranking and/or polling questions. Participants will be encouraged to share their experiences, perspectives on the importance of criteria for MAEIs and recommendations for additional criteria. The concluding period will allow for wrap up, opportunities for questions and answers and examine recommendations for the next steps.