OBJECTIVES: Analysis of the volume and structure of consumption of diuretics in Ukraine during 2019-2021.

METHODS: Assessment of drug consumption was performed according to the ATC / DDD method using the international index DDD / 1000 inhabitants / day (DID). The number of packages of drugs is taken from the information system "Pharmexplorer" of the company "Morion" (December 2022), and DDD for drugs - from the WHO website.

RESULTS: The market of diuretics in Ukraine is represented by four main groups of drugs: thiazide and thiazide-like diuretics, herbal drugs, loop and potassium-sparing diuretics. In 2021, 11 INN diuretics were registered in Ukraine. The total consumption of diuretics for 2019-2021 amounted to 15.83 DID - in 2019, 15.98 DID - in 2020 and 16.36 DID - in 2021. The undisputed leader in the Ukrainian market is the loop diuretic furosemide. The consumption of furosemide for these years ranged from 4.79 to 5.24 DID. In second place in terms of frequency of consumption was potassium-sparing diuretic spironaloctone with a rate of 3.07 to 3.60 DID. The third place was taken by the non-thiazide diuretic indapamide - 2.34-2.43 DID.

CONCLUSIONS: furosemide was the leader in consumption among diuretics in Ukraine. The DID of furosemide for 2019-2021 was 4.79-5.24 DID, due to its low cost, frequency of use, availability, relative safety and effectiveness.