OBJECTIVES: to analyze the development of lists of topical antifungal drugs (TAD) included into the all editions of State Formulary of Ukraine (SFU).

METHODS: information and comparative analysis.

RESULTS: SFU 1^st edition was launched in 2009. Currently 11 editions have been published. TAD have been included into the Chapter 9 “Dermatovenerology” of all editions. SFU 1^st contained 88 TAD (trade names), among them 85 were single active ingredient preparations; SFU 2^nd – 85 (82 single active ingredient drugs), SFU 3^rd – 69 (67), SFU 4^th – 84 (82), SFU 5^th – 74 (72), SFU 6^th – 66 (64), SFUs 7^th and 8^th – 44 (42 in both editions), SFUs 9^th and 10^th – 42 (40), 11^th – 43 (41). Number of preparations was reducing in the next sequence: SFU 1^st contained 17 INNs, SFUs 2^nd and 3^rd – 14, SFUs 4^th and 5^th – 11, SFUs 6^th – 10, SFUs 7^th-10^th – 9, and SFU 11^th – 8. The following preparations have been included into the all editions: bifonazole, clotrimazole, econazole, ketoconazole, miconazole, nystiatin, terbinafine and combination of natamycin, neomycin sulfate, hydrocortisone. Starting from SFU 1^st, these preparations have been excluded: griseofulvin, undecylenic acid, clorchinaldol, cetrimide, naftifine, methylene blue, salicylic acid, isoconazole, combination of benzoic acid, ethanol, potassium thiocyanate. Part of domestic TAD in the editions: SFU 1^st – 39%, SFU 2^nd – 38%, SFU 3^rd – 39%, SFU 4^th – 48%, SFU 5^th – 53%, SFU 6^th – 55%, SFUs 7^thand 8^th – 41%, SFUs 9^th – 38%, SFU 10^th – 45%, 11^th – 44%.

CONCLUSIONS: The tendency for reducing the number of TAD included into SFU is observed. Comparing to SFU 1^st, the number of TAD in SFU 11^th decreased twice. The preference is given to single active ingredient preparations. Part of domestic TAD is quite similar in the all SFU editions.