Dr Fleurence is a Senior Advisor to Dr. Francis Collins at the National Institutes of Health where her team is spearheading a national initiative to eliminate Hepatitis C in the United-States. Dr Fleurence is also affiliated with the National Institute of Biomedical Imaging and Bioengineering (NIBIB) where she is focused on advances in Artificial Intelligence and Machine Learning. Dr Fleurence currently co-leads the ISPOR Task Force on the suitability of EHR data for Health Technology Assessments. Previously, Dr Fleurence served as a senior health policy advisor in the Biden-Harris White House. Prior to her role at the White House, Dr Fleurence served as Senior Advisor to the NIH Director at the NIH. As part of the federal response to COVID-19, Dr. Fleurence led the novel “Say Yes! Covid Test”. This program was the first of its kind in to provide free rapid antigen tests to communities across the country. Dr. Fleurence served on the White House Pandemic Testing Board policy group, and the White House Office of Science Technology Policy (OSTP) Pandemic Innovation Task Force in 2021-2022. In 2021 and 2022, Dr. Fleurence was a recipient of three NIH Director’s Award for exceptional dedication and innovation in advancing COVID-19 testing and diagnostics efforts. In 2022, Dr. Fleurence was a recipient of the Health and Human Services Secretary’s award for Distinguished Service. She was the recipient of the 2023 “National Champion for Global Hepatitis Elimination” along with Dr Francis Collins.

Prior to her role at the White House and NIH, Dr. Fleurence served as the Executive Director of the National Evaluation System for health Technology Coordinating Center (NESTcc), and served as the Program Director for PCORnet at the US Patient-Centered Outcomes Research Institute (PCORI). Dr. Fleurence received a BA from Cambridge University (United Kingdom), an MA in business management from ESSEC-Paris (France), and an MSc in health economics and PhD in health sciences, both from the University of York (United Kingdom).