Manuela A. Joore graduated from Health Policy, Economics and Management (Maastricht University) in 1996. Following her graduation she has worked as a researcher in the field of Health Technology Assessment at the Maastricht University Medical Center and Maastricht University. She got her PhD in Economics in 2002 (Maastricht University) on the topic of health economic evaluation. Since 2006 Manuela has been teaching methods of Health Technology Assessment at Maastricht University and at other organizations. She is the developer and coordinator of the 'Cost-effectiveness modelling methods' course of the Health Sciences Research Master. She is a member of the 'Scientific Advisory Committee' of the National Health Care Institute, She is also a member of the 'Rational Pharmacotherapy' committees of the Netherlands Organisation for Health Research and Development (ZonMw). She is on the HTA board of the Dutch Centre for Personalised Cancer Treatment. Manuela leads a health economics evidence review group for the National Institute for Health and Care Excellence in the United Kingdom. She holds a Chair on 'Health Technology Assessment and decision-making' at Maastricht University. Her research focus is on (mostly model-based) health economic evaluation in a large variety of clinical areas. She uses economic evaluation to inform decision making regarding the (further) development, reimbursement, and use of health care technologies. She is (co-)author of over 120 peer-reviewed papers and is/was supervisor of 16 PhD students. She is involved in numerous Health Technology Assessment studies as an HTA-project leader and promotor. The total number of national and international grants obtained as a (co-)applicant adds up to more than 30 with a total sum of more than 13 million Euros.